Aucubin, an iridoid glucoside, exhibits significant protective activities against Amanita poisoning in beagle dogs. The post-injection of aucubin helps beagles survive from lethal poisoning caused by Amanita virosa. Protective activities of aucubin result from primarily preventing hepatic injury caused by Amanita poisoning, and is partly due to a protective effect of aucubin on the depression of m-RNA biosynthesis in the liver caused by α-amanitin intoxication.
Yamaura Y., Chang I. -M. (1995): Protective action against Amanita poisoning by iridoid glucoside, aucubin. – Czech Mycology 48(1): 67–72.
