Effects of three mutagens on spores of Aspergillus niger NG 233 were compared. After treatment with UV light and N-Methyl-N’-nitro-N-nitrosoguanidine, significant differences of citric acid production amongst isolates were detected; N-Ethyl-N-nitrosourea was the least effective mutagen. A maximum increase of 13% over the high productivity of the original strain was recorded for UV light as mutagen. In general, storage of spores decreased the activity of a series of strains with the exception of the isolate UV 6, which retained its activity of citric acid production.
Musílková M., Ujcová E., Seichert L., Sikyta B., Krumphanzl V. (1982): A comparison of the effect of mutagens on a high citric acid producing strain of Aspergillus niger. – Česká Mykologie 36(1): 47–51.
