A set of cultures of stromatic lignicolous Pyrenomycetes was screened for antibiotic activity. From a total of 25 species (36 strains), the antibiotic activity was detected in 9 species. The most active species were Diaporthe impulsa, D. pustulata, Hypoxylon multiforme, Hypoxylon sp. and Valseutypella tristicha. However, the antibiotic activity lowered down in the course of re-inoculation, especially when the cultures were transferred into the submerged conditions. According to this finding, more appropriate test would be the direct screening of the submerged cultures.
Prášil K., Šašek V. (1977): Antibiotic activity of some Pyrenomycetes. – Česká Mykologie 31(1): 1–7.