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Search for "SURYANARAYANAN T.S.": 2 articles found.
PANCHAL S., MURALI T.S., SURYANARAYANAN T.S., SANYAL K. (2022): Hypersaline fungi as a source of potentially active metabolites against pathogenic Candida species. [antifungal, bioprospecting, filamentous fungi, extremotolerant, hypersaline environment.] Czech Mycology 74(1): 93-101 (published: 22nd April, 2022)
abstract
Opportunistic and nosocomial human infections by various Candida species are of serious global health concern especially due to the spread of drug resistant strains and lack of treatment options. One of the main problems of bioprospecting for novel antimycotics is the rediscovery of already known molecules. To reduce the chances of such rediscoveries, one option is to search for unique metabolites from microbes of less studied and extreme habitats. Thirty-five fungal strains were isolated from solar salterns and the methanolic extracts of their culture supernatants were tested for the inhibition of human-pathogenic Candida albicans, C. dubliniensis, C. glabrata, C. lusitaniae, C. tropicalis, and two clinical isolates of C. auris. Of the fungi screened, two, viz. Curvularia nodosa and Fusarium cf. foetens, showed significant growth inhibition of all the Candida species. Although the effective molecules were not identified in this preliminary screening, it highlights the importance of bioprospecting fungi from extreme environments which have been neglected in the search for novel antibiotics.
GIRIVASAN K.P., SURYANARAYANAN T.S. (2004): Intact leaves as substrate for fungi: distribution of endophytes and phylloplane fungi in rattan palms. [phylloplane fungi, endophytes, Calamus, India] Czech Mycology 56(1-2): 33-43 (published: 12th August, 2004)
abstract
Leaves of twelve species of Calamus from southern India were screened simultaneously for the presence of phylloplane and endophytic fungi. Sampling of 2400 leaf segments yielded 824 endophyte isolates belonging to 34 species. Thirty species of phylloplane fungi were recorded. Several fungal species were found to be shared as endophytes by different hosts. However, the overlap between endophyte assemblage and phylloplane fungi of each host was low, suggesting that these two distinct groups of fungi occupy different niches, there by avoiding competition.
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