The ciliostatic activity of the heat-stable (100°C/10 min.) and chloroform-extractable metabolites of 63 strains of filamentous fungi - growing on the liquid medium - on tracheal cilia of one-day-old chickens in vitro was evaluated. Twenty two (34.9%) from the investigated strains produced ciliostatic metabolites, 4.7%, 7.9%, 3.1%, resp. 19.0% of the strains stopped the movement of cilia after 24, 48, 72, resp. 144 hours. The results are discussed in connection with chronic bronchitis of people working with moulded materials or living in moulded dwellings.
Piecková E., Jesenská Z. (1994): The effect of the heat-stable and chloroform-extractable secondary metabolites of filamentous fungi on the respiratory tract cilia movement of one-day-old chickens in vitro. – Czech Mycology 47(3): 215–221.
